Eze, 24, who impressed with his performances at Crystal Palace, was the only uncapped player included in the 25-man squad for the two Group C matches.
England will face Malta away and North Macedonia at home in their quest to qualify for the European Championship.
Alongside Eze, the Brighton & Hove Albion defender lewis dunk won a call-up after already earning a cap for England in 2018. Additionally, Aston Villa defender Tyrone Mings has returned to the squad.
However, there was no place in the squad for Chelsea striker Raheem Sterling, who hasn’t received a call-up for the upcoming qualifier.
England currently sit top of Group C after impressive away wins against Italy and Ukraine in their previous fixtures.
Eze’s inclusion in the national team highlights his growing stature in English football and gives him the opportunity to showcase his skills on the international stage.
Fans will be eagerly awaiting his potential debut and hoping for a successful campaign as England continue their journey towards Euro 2024 qualification.
Guardians: Sam Johnstone (Crystal Palace), Jordan Pickford (Everton), Aaron Ramsdale (Arsenal)
Defenders: Trent Alexander-Arnold (Liverpool), Lewis Dunk (Brighton & Hove Albion), Marc Guehi (Crystal Palace), Harry Maguire (Manchester United), Tyrone Mings (Aston Villa), Luke Shaw (Manchester United), John Stones (Manchester City) ), Kieran Trippier (Newcastle United), Kyle Walker (Manchester City)
Midfielders: Jude Bellingham (Borussia Dortmund), Eberechi Eze (Crystal Palace), Conor Gallagher (Chelsea), Jordan Henderson (Liverpool), Kalvin Phillips (Manchester City), Declan Rice (West Ham United)
Forwards: Phil Foden (Manchester City), Jack Grealish (Manchester City), Harry Kane (Tottenham Hotspur), James Maddison (Leicester City), Marcus Rashford (Manchester United), Bukayo Saka (Arsenal), Callum Wilson (Newcastle United)